Official word from Konami indicates an issue with Hideo Kojima’s new opus Metal Gear Solid V: The Phantom Pain has arisen, and it doesn’t appear to be specific to any one hardware.
The details behind it are rather fague, but the progression glitch seems to revolve around using Quiet as a buddy in two particular missions. The official statement, care of Konami’s UK support site, is as follows:
In "METAL GEAR SOLID V: THE PHANTOM PAIN" which was released on September 1st, 2015 there is a possibility that the game stops progress if having Quiet as a buddy while playing "Mission 29" or "Mission 42". This situation can be avoided by not using Quiet as a buddy while playing either "Mission 29" or "Mission 42".
We deeply apologize, and appreciate your patience for further announcements regarding this issue.
This issue is known to be present for Xbox360, XboxOne, PlayStation®3, PlayStation®4 and Steam®.
MGS V has already sold 3 millions units since last Tuesday, and the vast majority of them have been on the PlayStation 4. However, much like most major titles, issues have surfaced for MGS V as well, with this progression glitch joining with the latent server issues, which are still being ironed out.
Nothing in the statement indicates that a fix is upcoming, but Konami is aware of what’s taking place. We will keep updated on the situation and indicate more information as it arises.